Search results for "Invasive candidiasi"

showing 9 items of 9 documents

Optimal doses of caspofungin during continuous venovenous hemodiafiltration in critically ill patients

2017

0301 basic medicineContinuous renal replacement therapymedicine.medical_specialtyLetterCritical Illness030106 microbiologyHemodiafiltrationCritical Care and Intensive Care MedicineEchinocandinsLipopeptides03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCaspofunginHumansMedicineIntensive care medicinebusiness.industryCritically illlcsh:Medical emergencies. Critical care. Intensive care. First aid030208 emergency & critical care medicinelcsh:RC86-88.9Invasive candidiasisContinuous venovenous hemodiafiltrationAcute Kidney Injurymedicine.diseaseInvasive candidiasisRenal Replacement TherapychemistryAdsorptionCaspofunginbusinessCritical Care
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MEDical wards Invasive Candidiasis ALgorithms (MEDICAL):Consensus proposal for management

2016

Abstract Introduction A majority of invasive Candida infections occur in medical wards; however, evidence for management in this setting is scarce and based primarily on the intensive care or surgical setting. On behalf of the Italian Society for Anti-Infective Therapy (SITA) and the Italian Federation of Associations of Hospital Doctors on Internal Medicine (FADOI), the MEDICAL group produced practical management algorithms for patients in internal medicine wards. Methods The MEDICAL group panel, composed of 30 members from internal medicine, infectious disease, clinical pharmacology, clinical microbiology and clinical epidemiology, provided expert opinion through the RAND/UCLA method. Res…

0301 basic medicineMedical wardAntifungal AgentsConsensusInvasiveCritical CareDelphi TechniqueClinical severity; Invasive candidiasis; Medical wards; Risk stratification; Algorithms; Antifungal Agents; Candidiasis Invasive; Consensus; Critical Care; Delphi Technique; Early Diagnosis; Echinocandins; Humans; Internal Medicine; Italy; Practice Guidelines as Topic; Severity of Illness Index; Internal Medicine030106 microbiologyeducationDelphi methodInvasive candidiasiSettore MED/17 - MALATTIE INFETTIVESeverity of Illness Indexlaw.invention03 medical and health sciencesEchinocandins0302 clinical medicinelawIntensive careSeverity of illnessMedical consensusInternal MedicineMedicineHumansCandidiasis InvasiveClinical severity030212 general & internal medicineRisk stratificationcomputer.programming_languageClinical pharmacologybusiness.industryCandidiasisClinical severity; Invasive candidiasis; Medical wards; Risk stratificationInvasive candidiasismedicine.diseaseMedical wardsInvasive candidiasisEarly DiagnosisItalyInfectious disease (medical specialty)Practice Guidelines as TopicbusinessClinical severity; Invasive candidiasis; Medical wards; Risk stratification; Internal MedicinecomputerAlgorithmDelphiAlgorithms
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Performance of existing clinical scores and laboratory tests for the diagnosis of invasive candidiasis in critically ill, nonneutropenic, adult patie…

2022

Background The Fungal Infections Definitions in Intensive Care Unit (ICU) patients (FUNDICU) project aims to provide standard sets of definitions for invasive fungal diseases in critically ill, adult patients. Objectives To summarize the available evidence on the diagnostic performance of clinical scores and laboratory tests for invasive candidiasis (IC) in nonneutropenic, adult critically ill patients. Methods A systematic review was performed to evaluate studies assessing the diagnostic performance for IC of clinical scores and/or laboratory tests vs. a reference standard or a reference definition in critically ill, nonneutropenic, adult patients in ICU. Results Clinical scores, despite t…

AdultAntifungal AgentsCritical CarediagnosisCritical IllnesscandidemiaDermatologyGeneral Medicineinvasive candidiasisIC.Intensive Care UnitsInfectious DiseasesCandida; biomarker; candidaemia; deep-seated candidiasis; diagnosis; invasive candidiasisHumansbiomarkercandidaemiaCandidiasis InvasiveProspective Studiesdeep-seated candidiasisCandida
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Untargeted Antifungal Treatment Strategies for Invasive Candidiasis in Non-neutropenic Critically Ill Patients: Current Evidence and Insights

2017

Purpose of Review: The purpose of this study was to provide an overview and insights on important new concepts on untargeted antifungal treatment strategies, namely prophylaxis pre-emptive and empiric treatments for the management of invasive candidiasis (IC) in non-neutropenic critically ill patients. Recent Findings: Recently, clinical practice guidelines provided recommendation for the management of IC. However, results from recent trials and systematic reviews questioned the effect of untargeted antifungal treatment strategies, especially in terms of survival benefits in non-neutropenic patients, even with septic shock. Summary: Widespread use of untargeted antifungal treatment strategi…

Antifungalmedicine.medical_specialtyEmpiric treatmentmedicine.drug_classInvasive candidiasiBiology03 medical and health sciences0302 clinical medicineInvasive fungal infectionmedicine030212 general & internal medicineAntifungal treatmentMED/41 - ANESTESIOLOGIAIntensive care medicineCandida infectionCritically illCandidemia030208 emergency & critical care medicineInvasive candidiasismedicine.diseaseNon neutropenicClinical PracticeInvasive candidiasisInfectious DiseasesSystematic reviewTreatment strategyAntifungal treatment; Candida infection; Candidemia; Empiric treatment; Invasive candidiasis; Invasive fungal infectionEmpiric treatment
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European expert opinion on the management of invasive candidiasis in adults

2011

Item does not contain fulltext This report discusses the present status of antifungal therapy and treatment options for candidaemia, considered by experts in the field in Europe. A conference of 26 experts from 13 European countries was held to discuss strategies for the treatment and prevention of invasive candidiasis, with the aim of providing a review on optimal management strategies. Published and unpublished comparative trials on antifungal therapy were analysed and discussed. Commonly asked questions about the management of candidaemia were selected, and possible responses to these questions were discussed. Panellists were then asked to respond to each question by using a touchpad ans…

Invasive mycoses and compromised host Translational research [N4i 2]AdultMicrobiology (medical)medicine.medical_specialtyAntifungal Agentsmedicine.medical_treatmentPlacebo-controlled studyMEDLINEInvasive mycoses and compromised host Infection and autoimmunity [N4i 2]MicrobiologyMedicineHumanscandidaemiaCandidiasis InvasiveguidelinesIntensive care medicineWatchful Waitingtherapybusiness.industryTreatment optionsPathogenesis and modulation of inflammation Infection and autoimmunity [N4i 1]General MedicineInvasive candidiasisComparative trialAntibiotic Prophylaxismedicine.diseaseOptimal managementEuropeIntensive Care UnitsInfectious DiseasesconsensusExpert opinioncandidabusinessWatchful waitingClinical Microbiology and Infection
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Epidemiology of invasive candidiasis in a surgical intensive care unit: an observational study

2015

Background: Invasive candidiasis (IC) is a frequent and life-threatening infection in critically ill patients. The aim of this study was to evaluate the epidemiology of IC and the antifungal susceptibility of etiological agents in patients admitted to our surgical intensive care unit (SICU) in Spain. Methods: We designed a prospective, observational, single center, population-based study in a SICU. We included all consecutive adult patients (≥18 years old) who had documented IC, either on admission or during their stay, between January 2012 and December 2013. Results: There were a total of 22 episodes of IC in the 1149 patients admitted during the 24-month study. The overall IC incidence wa…

Malemedicine.medical_specialtyAntifungal AgentsPopulationMicrobiologiaMicrobial Sensitivity TestsCandida parapsilosisGeneral Biochemistry Genetics and Molecular Biologylaw.inventionCandida tropicalisDrug Resistance FungallawInternal medicineCandida kruseiAbdomenmedicineHumansSurgical Wound InfectionIntensive care unitCandidiasis InvasiveCandida albicanseducationEpidemiologiaAgedCandidaMedicine(all)education.field_of_studyCandida glabratabiologybusiness.industryBiochemistry Genetics and Molecular Biology(all)CandidemiaGeneral MedicineFongs patògensMiddle Agedbiology.organism_classificationIntensive care unitSurgeryInvasive candidiasisIntensive Care UnitsTreatment OutcomeSpainFemalebusinessAntifungal susceptibilitySurgery Department HospitalFluconazoleResearch Articlemedicine.drugBMC Research Notes
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Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study

2022

INTRODUCTION: Intra-abdominal infections represent the second most frequently acquired infection in the intensive care unit (ICU), with mortality rates ranging from 20% to 50%. Candida spp. may be responsible for up to 10-30% of cases. This study assesses risk factors for development of intra-abdominal candidiasis (IAC) among patients admitted to ICU. METHODS: We performed a case-control study in 26 European ICUs during the period January 2015-December 2016. Patients at least 18 years old who developed an episode of microbiologically documented IAC during their stay in the ICU (at least 48 h after admission) served as the case cohort. The control group consisted of adult patients who did no…

Microbiology (medical)MORTALITYInvasive candidiasiCandida; Intra-abdominal infection; Invasive candidiasis; Risk factorsCONTROLLED-TRIALCASPOFUNGINCANDIDEMIAInvasive candidiasisInfectious Diseaseslnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]Intra-abdominal infectionRisk factorsINFECTIONSMANAGEMENTEPIDEMIOLOGYPREDICTORSCONSENSUSCRITICALLY III PATIENTSCandida
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Performance of existing definitions and tests for the diagnosis of invasive fungal diseases other than invasive candidiasis and invasive aspergillosi…

2021

Diagnòstic; Malalties fúngiques invasores; Pneumocystis Diagnóstico; Enfermedades fúngicas invasivas; Pneumocystis Diagnosis; Invasive fungal diseases; Pneumocystis The Fungal Infections Definitions in Intensive Care Unit (ICU) patients (FUNDICU) project aims to provide standard sets of definitions for invasive fungal diseases (IFDs) in critically ill, adult patients, including invasive aspergillosis (IA), invasive candidiasis (IC), Pneumocystis jirovecii pneumonia (PJP), and other non-IA, non-IC IFDs. The first step of the project was the conduction of separated systematic reviews of the characteristics and applicability to critically ill, adult patients outside classical populations at ri…

diagnosis:infecciones bacterianas y micosis::micosis::infecciones fúngicas invasoras [ENFERMEDADES]invasive fungal diseasesPJPPlant ScienceAspergillosis:Bacterial Infections and Mycoses::Mycoses::Invasive Fungal Infections [DISEASES]law.invention0302 clinical medicineIFD; PJP; biomarker; diagnosis; invasive fungal diseases; pneumocystislawDiagnosis:Other subheadings::/diagnosis [Other subheadings]Medicine and Health Sciences030212 general & internal medicinelcsh:QH301-705.50303 health sciences:Natural Science Disciplines::Science::Research::Empirical Research::Qualitative Research [DISCIPLINES AND OCCUPATIONS]EcologyCommunicationPneumocystis jirovecii PneumoniaInvasive candidiasisIntensive care unitInvasive fungal diseasesSystematic reviewbiomarkerIFDMicrobiology (medical)medicine.medical_specialtyEvolutionQualitative evidence:Otros calificadores::/diagnóstico [Otros calificadores]pneumocystisInvestigació qualitativa03 medical and health sciencesBehavior and Systematics:disciplinas de las ciencias naturales::ciencia::investigación::investigación empírica::investigación cualitativa [DISCIPLINAS Y OCUPACIONES]medicineIntensive care medicineEcology Evolution Behavior and SystematicsAdult patients030306 microbiologyCritically illbusiness.industryPneumocystisBiomarker; Diagnosis; IFD; Invasive fungal diseases; PJP; PneumocystisBiomarkermedicine.diseaselnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]lcsh:Biology (General)Micosi - Diagnòsticbusiness
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Procalcitonin for the diagnosis of invasive candidiasis: what is the evidence?

2017

Abstracts Procalcitonin is a widely used marker for the evaluation of infection and sepsis and to guide antibiotic therapy. During the last decade, several studies evaluated its role and diagnostic performance as a surrogate marker for the identification of Candida spp. in suspected invasive candidiasis. A low serum level and a favorable negative predictive value are the main findings for procalcitonin in this setting. The aim of this report is to provide an updated brief summary of the evidence supporting the use of PCT for the management of invasive candidiasis.

medicine.medical_specialtySepsiInvasive candidiasiCritical Care and Intensive Care MedicineProcalcitoninSepsis03 medical and health sciences0302 clinical medicineAntibiotic therapySepsismedicine030212 general & internal medicineIntensive care medicineLetter to the EditorCandida spp.Surrogate endpointbusiness.industrylcsh:Medical emergencies. Critical care. Intensive care. First aid030208 emergency & critical care medicineInvasive candidiasislcsh:RC86-88.9medicine.diseasebacterial infections and mycosesCandida spp.; Invasive candidiasis; Procalcitonin; Sepsis; Critical Care and Intensive Care MedicinePredictive valueInvasive candidiasisCandida sppbusinessProcalcitoninhormones hormone substitutes and hormone antagonistsJournal of Intensive Care
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